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After one hour of rest following completion of therapy, the patients were visually checked for any abnormalities using an anoscope and subsequently discharge to home. Only the items with a P value of less than 0. The incidence of fever was 4. The results are presented in table 2. ALTA therapy has a strong therapeutic effect, which will be used widely in other countries just as well as Japan. The fact that this study revealed findings related to complications is significant. This means that young patients, patients undergoing ALTA therapy for a second time, or patients receiving a large ALTA dosage are susceptible to developing fever.

However, no feasible preventive measures exist for physicians to employ against these three factors prior to therapy. We should inform patients of the high likelihood of developing fever following the therapy and prescribe draft of antipyretic analgesics. Two issues should be noted in regard to the results of this study.

These are the incidence of fever and the severity of fever. As for the severity of fever, we saw cases of fever as high as To date, no papers have discussed the mechanism behind fever following ALTA therapy. We speculate that complications arise from the difficulty that young patients have resting after therapy and the progressive increases in total dosages injected. Finally, we must mention the limitations and issues associated with this study. This was a retrospective study. We cannot discuss any fever that developed subsequent to the day after therapy.

The significant risk factors for fever following ALTA therapy that were found in this study appear to be of great interest and strong significance. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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For Authors We aim to bring about a change in modern scholarly communications through the effective use of editorial and publishing polices. This settled, Dick returns to his Owl in Daylight plot. Either way, poor Ed is then kidnapped and bopped on the head in an alley, and the biochip is then implanted in his brain with the alien consciousness inside.

Meanwhile, the alien in his brain is listening now to music for the first time ever. Utterly blissful. Except for one thing… Ed has terrible taste. Furious, the biochip decides to take matters into its own circuitry. He feeds Ed more and more advanced mathematical ideas, which Ed uses to compose more and more outstanding, serious work for the alien to enjoy. He goes in for a brain scan—at which point the doctors locate the biochip in his head. The alien then addresses Ed and confesses to him what has been going on.

Dick likens this moment to Flowers for Algernon , which he tells Lee he finds very moving. But, wait, another twist. A happy ending, Lee wonders? Yes, Dick agrees, but well, actually, no.

And Ed will, of course, have to die along with the new Christ-alien. But dies at the very moment that his hand closes on it.

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Death and victory become one event for the Faustian man. This is the Faustian victory. At this point Lee asks if the new alien, carrying Ed carrying the original alien , could just biochip someone else. Or re-biochip the first alien—did he die, or what? Swiftly, Dick devolves into a discussion about cloning and whether or not putting yourself on the biochip necessarily kills you, and on and on. Later, Dick and Lee resume their discussion, weirdly, right back at the beginning again.

He re-explains the origin of the title The Owl in Daylight and the idea of it being Faustian, almost as if he had not just explained it all five days earlier. Has he forgotten? This time, however, Dick moves further into the underlying and personal meaning of the bargain that Ed will be making.

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So that you could look on the graph, you can see that those two lines are going to meet and finally the cost line is going to be higher than the yield line—the cost line is going to be higher than the yield line, you know. Neither of them draw any connection to his struggle with amphetamine addiction during the same period. Instead, Dick just reflects that his own physical stamina has been declining. When I got finished, I was living on aspirin, scotch, and potassium tablets.

He feared dying of a heart attack. In a letter he recounted driving his car intentionally into the metal support beam of a parking garage. He continued to receive visions and to hear voices. A few weeks after his interview with Lee, Dick mentioned to his therapist that he was having trouble with his vision. The next day he was found there, on the floor, having had a stroke. A few days later, now in the hospital, he had a second stroke and became brain dead.

Five days later, he was taken off life support and died on March 2, Yes, his final novel, The Transmigration of Timothy Archer would not sell terribly well. At first the posthumous reprintings of his other novels failed to attract many fresh readers.

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But it also galvanized a new generation of dedicated Philip K. Dick fans, science fiction aficionados turned on by Star Wars and Star Trek but now ready for something grittier, darker, and deeper. The computer resents this, since it prefers to solve abstract, theoretical problems of the highest order. Now the scientist, trapped in his own amusement Park and subject to the mind of the misused misused and knowing it and keenly resenting it must solve the maze that the Park represents and find his way out of it by solving problems propounded by the computer and presented to him in sequence.

Dick leaves open the possibility that some other version would have prevailed, perhaps some kind of amalgamation of the two. In an interview with The Twilight Zone magazine , Dick spoke to his eventual plans to merge the two books.

I really enjoy doing that, a paste-up job. A synthesis, in other words. In she self-published a novel by the same name, in an effort to complete the project that Dick originally intended. Her planned sequel, The Owl in Twilight, would build on her own ideas. In the end, the Philip K.

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Dick estate, managed by his two daughters, asked Tessa to take down the publication and she obliged. But a few years later, in an interview with Collider , Giamatti described the complicated process behind the Dick biopic:.